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According to American Society of Gene Therapy; Gene Therapy can be defined as the use of genetic material (usually DNA, RNA or oligonucleotide) to manipulate a patient's cells for the treatment of an inherited or acquired disease. Accordingly, Cell Therapy can be defined as the infusion or transplantation of whole cells into a patient for the treatment of an inherited or acquired disease. Thus, Gene Therapy and Cell Therapy are considered to be overlapping fields of biomedical research with similar therapeutic goals. In some instances, disease management requires combined use of gene and cell therapy approaches as in SCID therapy.